My 2wd got up to 25mpg on the highway, as long as kept the RPMs under 2000 (About 55-56 mph). But my 4wd is heavier, has bigger tires and lower gears, so the most I get out of it is about 21mpg (again, under 2000 RPMs, which, with the lower gearing, is about 52-53 mph). Around town I average about 16mpg, a little lower if keep my foot in it more often (hey, it happens; if I was worried about mileage I wouldn't be driving a 4500 lb SUV). All told, the mileage isn't bad for a vehicle this size that was designed over 10 years ago. Although I do wish we'd see a new generation with a direct gas injection engine or the turbo diesel from the new Frontier.